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Home › Conditions › Autism Spectrum Disorder

Autism Spectrum Disorder

57 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Autism Spectrum Disorder

191 trials tracked for Autism Spectrum Disorder: 28 in phase 3 or 4 and 8 with published results. The most-cited published study has 118 citations.

191Trials tracked
28Phase 3 & 4
0Recruiting
8With published results
Phase distribution
Phase 4 11 Phase 3 17 Phase 2 52 Phase 1 10 Other / NA 101
  1. Phase 3 Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD) Completed · 118 cited
  2. Phase 4 Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders Completed · 45 cited
  3. Phase 3 Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder Completed · 45 cited
  4. Phase 3 Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism Completed · 45 cited
  5. Phase 3 Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders Completed · 31 cited
  6. Phase 4 Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD Completed · 12 cited
Show 44 more trials
  1. Phase 3 Pediatric Open-Label Extension Study Completed · 11 cited
  2. Phase 3 A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study) Completed · 7 cited
  3. Phase 4 Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot Study Completed
  4. Phase 4 Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of Autism Completed
  5. Phase 4 Improving Driving in Young People With Autism Spectrum Disorders Completed
  6. Phase 4 Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD) Completed
  7. Phase 4 Atomoxetine, Placebo and Parent Management Training in Autism Completed
  8. Phase 4 A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders Completed
  9. Phase 4 FMRI Brain Activation of Aripiprazole Treatment in Autism Spectrum Disorders Completed
  10. Phase 4 A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic Disorder Completed
  11. Phase 4 Minocycline to Treat Childhood Regressive Autism Completed
  12. Phase 3 Study of Paliperidone ER in Adolescents and Young Adults With Autism Completed
  13. Phase 3 Folinic Acid in Autism Completed
  14. Phase 3 A Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder Completed
  15. Phase 3 Treatment of Encopresis in Children With Autism Spectrum Disorders Completed
  16. Phase 3 Intranasal Vasopressin Treatment in Children With Autism Completed
  17. Phase 3 Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children Completed
  18. Phase 3 Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders Completed
  19. Phase 3 Pilot Study of the Effect of Hyperbaric Oxygen Treatment on Behavioral and Biomarker Measures in Children With Autism Completed
  20. Phase 3 Lurasidone Pediatric Autism Study Completed
  21. Phase 3 Pharmacogenomics in Autism Treatment Completed
  22. Phase 3 A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms Completed
  23. Phase 2 A Study of Oxytocin in Children and Adolescents With Autistic Disorder Completed
  24. Phase 2 Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder Completed
  25. Phase 2 Fatty Acid Supplementation in Children With ASD Completed
  26. Phase 2 Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain Completed
  27. Phase 2 A Trial of Sertraline in Young Children With Autism Spectrum Disorder Completed
  28. Phase 2 Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism Completed
  29. Phase 2 Nuedexta for the Treatment of Adults With Autism Completed
  30. Phase 2 Intranasal Oxytocin Treatment for Social Deficits in Children With Autism Completed
  31. Phase 2 Acamprosate in Youth With Fragile X Syndrome Completed
  32. Phase 2 Rapalogues for Autism Phenotype in TSC: A Feasibility Study Completed
  33. Phase 2 Safety of L1-79 in Adolescent and Adult Males With Autism Completed
  34. Phase 2 Intranasal Oxytocin and Learning in Autism Completed
  35. Phase 2 Allogenic Cord Blood Transfusion in Patients With Autism Completed
  36. Phase 2 Open-label Study of Safety and Tolerability of Memantine in Children With Autism Completed
  37. Phase 2 Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors Completed
  38. Phase 2 University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial Completed
  39. Phase 2 Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD) Completed
  40. Phase 2 ScanBrit Dietary Intervention in Autism Completed
  41. Phase 2 Omega-3 Fatty Acids for Hyperactivity Treatment in Autism Spectrum Disorder Completed
  42. Phase 2 Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders Completed
  43. Phase 2 A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder Completed
  44. Phase 2 The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism Completed

Showing the 50 most-cited and recently-updated of 191 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Autism spectrum disorder diagnoses reported in children with possible prenatal Zika virus exposure in Puerto Rico
Pediatrics
Autism spectrum disorder diagnoses reported in children with possible prenatal Zika virus exposure in Puerto Rico Could prenatal Zika exposure be linked to autism diagnoses in children?
An observational report from Puerto Rico describes autism spectrum disorder diagnoses among children with possible prenatal Zika virus expos…
Health officials are tracking autism diagnoses in children with possible prenatal Zika exposure in Puerto Rico to see if a pattern emerges.
CDC Apr 4, 2026
Connectome models of attention and autism show phenotype-specific features vary by age and diagnosis
Psychiatry
Connectome models of attention and autism show phenotype-specific features vary by age and diagnosis How does the brain's wiring for attention differ from its wiring for autism traits?
An analysis of transdiagnostic connectome-based models across datasets found that models predicting sustained attention phenotypes shared mo…
Brain models for attention share more features with each other than with models predicting autism symptoms, showing these brain patterns dif…
medRxiv Apr 4, 2026
CDC surveillance estimates autism spectrum disorder prevalence among 8-year-olds in 11 U.S. sites
Psychiatry
CDC surveillance estimates autism spectrum disorder prevalence among 8-year-olds in 11 U.S. sites CDC estimates autism prevalence among 8-year-old children in 11 U.S. sites
A CDC surveillance summary reports estimated prevalence of autism spectrum disorder (ASD) among children aged 8 years across 11 U.S.
CDC estimates autism affects 8-year-olds in 11 U.S. sites, offering a snapshot of how common the condition is in these communities.
CDC Apr 3, 2026
Surveillance data on autism spectrum disorder prevalence in 8-year-old children across 11 US sites
Psychiatry
Surveillance data on autism spectrum disorder prevalence in 8-year-old children across 11 US sites How common is autism among 8-year-olds in the US? A new snapshot looks for answers
A surveillance summary from the Autism and Developmental Disabilities Monitoring Network reports on autism spectrum disorder prevalence and…
A new CDC snapshot tracks autism among 8-year-olds across 11 U.S. communities, offering a crucial look at how common the condition is today.
CDC Apr 3, 2026
Systematic review finds gaps in quality-of-life assessment tools for autistic adults without intellectual disability
Psychiatry Sys. Review
Systematic review finds gaps in quality-of-life assessment tools for autistic adults without intellectual disability How do we measure what makes life good for autistic adults?
A systematic review/mini-review examined the state of knowledge regarding quality-of-life assessment in autistic adults with lower support n…
Autistic adults without intellectual disability lack quality-of-life tools that capture their real challenges, leaving support services poor…
Frontiers Apr 3, 2026
CDC surveillance monitors early identification of autism spectrum disorder in 4-year-old children
Psychiatry
CDC surveillance monitors early identification of autism spectrum disorder in 4-year-old children CDC monitors early autism identification in 4-year-old children across six U.S. sites
A CDC surveillance summary from the Early Autism and Developmental Disabilities Monitoring Network reports on early identification of ASD am…
The CDC is tracking how early autism is identified in 4-year-olds across six U.S. sites to help public health professionals plan better supp…
CDC Apr 3, 2026
Surveillance data on early autism identification in 4-year-old children from US network
Psychiatry
Surveillance data on early autism identification in 4-year-old children from US network U.S. surveillance network tracks autism identification in 4-year-old children
A surveillance summary from the US Autism and Developmental Disabilities Monitoring Network reports on early identification of autism spectr…
The CDC reports on early identification of autism spectrum disorder among 4-year-olds across the United States.
CDC Apr 3, 2026
Meta-analysis: Children with ASD show poorer balance vs. TD peers, SMD -0.66 with observational tools
Pediatrics Meta-analysis
Meta-analysis: Children with ASD show poorer balance vs. TD peers, SMD -0.66 with observational tools Do kids with autism have more trouble with balance? A review of 34 studies suggests they do
A meta-analysis of 34 studies (n=1278) found children and adolescents with autism spectrum disorder (ASD) had significantly poorer balance t…
Kids with autism often struggle with balance, making walking and playing harder, according to a review of 34 studies involving over 1,200 ch…
Mar 30, 2026
Perspective: Bilingualism myths harm autistic children from multilingual families, calls for culturally sustaining interventions
Psychiatry
Perspective: Bilingualism myths harm autistic children from multilingual families, calls for culturally sustaining interventions Why are autistic children from multilingual families still told to speak only English at home?
A perspective paper examines how historical misconceptions linking bilingualism with cognitive deficits became embedded in autism interventi…
Autistic children in multilingual families face harmful advice to drop their heritage language, despite proof it supports their development …
Frontiers Mar 30, 2026

Questions about Autism Spectrum Disorder

Do specific autism neurosubtypes show opposite electrical brain activity patterns in preclinical models?

Research using animal models and human EEG data indicates that autism consists of distinct neurosubtypes with opposing electrical brain activity patterns related to excitation and inhibition balance.

Full answer →
Does having different gut bacteria affect children with Autism Spectrum Disorder and ADHD?

Yes, children with ASD and ADHD often have different gut bacteria compared to neurotypical children, and this imbalance may influence symptoms and gut health.

Full answer →