AI applications in acute care showed potential but face significant implementation challenges.
AI Is Quietly Changing How ERs Save Lives. Here’s How.
This narrative review examined artificial intelligence (AI) applications in patients within emergency departments and intensive care units. …
Artificial intelligence is moving into emergency rooms to help doctors spot life-threatening problems faster, but it’s not ready to run the …
Macrophage glycolysis interactions modulate inflammation and polarization in sepsis
A Hidden Switch in Your Immune System Could Change Sepsis Treatment
This systematic review examined mechanisms linking macrophage glycolysis and inflammation in sepsis. Findings indicate that increasing aerob…
Understanding this biological energy switch gives researchers a clear new target to stop sepsis in its tracks.
NTIS subtypes and thyroid antibodies associated with higher in-hospital mortality in sepsis cohort
Thyroid Antibodies Signal Higher Death Risk in Sepsis
A retrospective cohort study of 871 sepsis patients at a Shanghai tertiary hospital found non-thyroidal illness syndrome (NTIS) was independ…
Thyroid antibodies found in sepsis patients signal a higher risk of death, offering doctors a critical warning sign beyond standard infectio…
Meta-analysis identifies clinical signs associated with sepsis and mortality in young infants
Which signs in a newborn's cry or feeding best warn of life-threatening infection?
A systematic review and meta-analysis of 52 studies including 140,885 young infants in resource-limited settings found 16 clinical signs sig…
A weak cry, poor feeding, or a drowsy baby are the top five signs linked to life-threatening infection and death in newborns under two month…
Socioeconomic factors associated with increased mortality in adults with sepsis or septic shock
Study finds poverty and lack of insurance linked to higher death rates from sepsis
A systematic review and meta-analysis of 13 observational studies involving 3,951,677 adults with sepsis or septic shock found that several …
Poverty and lack of private insurance are linked to higher death rates from sepsis, affecting nearly 4 million adults in a major review.
Report describes sepsis program activities in US acute care hospitals
What are hospitals actually doing to fight sepsis? A new report looks inside.
A report describes sepsis program activities in acute care hospitals across the United States. No specific study design, population size, in…
A new report reveals what hospitals are doing to fight sepsis, but it doesn't say which programs save lives or which are safest.
Meta-analysis finds diaphragmatic atrophy and weakness in critically ill patients on ventilation or with sepsis
Why do critically ill patients struggle to breathe on their own? Their diaphragm muscles shrink and weaken.
A systematic review and meta-analysis of 187 critically ill patients requiring mechanical ventilation or with sepsis found diaphragmatic fib…
Critically ill patients on ventilators have diaphragm muscles that are 30% smaller and dramatically weaker than normal, explaining their str…
Procalcitonin-guided antibiotic protocols reduce therapy duration in critically ill sepsis patients
Blood test helps guide antibiotic use in sepsis patients, may shorten treatment
A rapid systematic review and meta-analysis of 19 trials (n=6,382) in critically ill adult sepsis patients found procalcitonin-guided antibi…
A blood test that measures procalcitonin may help doctors safely shorten antibiotic treatment for sepsis by about two days.
Systematic review explores pathogenesis and emerging treatments for sepsis-induced cardiomyopathy
Review explores potential new treatments for sepsis-related heart problems
A systematic review examined the pathogenesis and treatment landscape for sepsis-induced cardiomyopathy in patients with severe sepsis. The …
New approaches targeting inflammation, calcium, and energy metabolism show potential for treating heart damage in severe sepsis patients.
PAC use in cardiogenic shock associated with lower mortality but higher sepsis risk in meta-analysis
Can a heart monitor help people survive cardiogenic shock?
A meta-analysis of 14 observational studies including 789,553 adults with cardiogenic shock found pulmonary artery catheterization (PAC) use…
A heart monitor linked to lower death rates in cardiogenic shock also raises infection risks and the need for stronger research.
Higher baseline chondroitin sulfate predicts greater mortality benefit from restrictive fluid strategy in sepsis
Blood marker may help predict which sepsis patients benefit from less fluid
A biomarker analysis within an RCT of 574 patients with sepsis-associated hypotension found that higher baseline plasma chondroitin sulfate …
A blood marker may help doctors decide which sepsis patients benefit most from receiving less intravenous fluid during treatment.
VR and in-person sepsis simulation show similar skill outcomes in medical student pilot study
Can virtual reality teach doctors to spot sepsis as well as real training?
A randomized comparative pilot study of 32 final-year medical students found no statistically significant differences in mQSAT scores or sep…
Virtual reality training helped medical students spot when patients needed intensive care better than traditional practice methods in a new …