Intermittent theta-burst stimulation of right putamen improves motor scores in Parkinson's disease patients.
New Non-Invasive Method Eases Parkinsons Motor Symptoms Without Surgery
This randomized controlled trial in 19 Parkinson's disease patients found that intermittent theta-burst transcranial temporal interference s…
A new non-surgical brain treatment showed promise in reducing movement problems for Parkinsons patients.
Meta-analysis links speech features to severity in Parkinsons, cerebral palsy, and ALS
Speech patterns may help track disease severity in Parkinsons and other conditions
This meta-analysis synthesizes evidence from 890 speakers across 5 languages to evaluate a training-free method for assessing speech degrada…
A new computer method tracks Parkinson's and other disease severity by measuring how specific speech sounds change without needing special t…
Prospective open-label study links brain MRI to impulse control changes after DBS for Parkinson's.
Can brain scans predict impulse problems after Parkinson's surgery?
This prospective open-label study of 35 patients with advanced Parkinson's disease undergoing subthalamic deep brain stimulation found that …
Healthy brain wiring in key areas may help predict who develops impulse control problems after Parkinson's deep brain stimulation surgery.
Review of flavonoids shows preclinical neuroprotective potential in Parkinson's disease models
Parkinson's drugs may need a new partner
This narrative review synthesizes preclinical evidence regarding flavonoids including baicalein, quercetin, apigenin, luteolin, and EGCG in …
Plant-based compounds could one day help treat Parkinson's by fixing multiple brain chemicals at once, not just dopamine.
Protocol for cane training trial in Parkinson's disease to assess gait speed and confidence.
Could simple cane training help people with Parkinson's walk faster and feel safer?
This is a protocol for a randomized controlled trial in 26 individuals with Parkinson's disease. It will compare cane training and use to gl…
A new trial tests whether four cane training sessions can help people with Parkinson's walk faster and feel safer, addressing freezing of ga…
Hypothesis links cumulative levodopa exposure to frailty and reduced healthspan in Parkinson's disease
Researchers propose cumulative levodopa exposure may increase health complications in Parkinson’s disease.
A hypothesis proposes that cumulative levodopa exposure in patients with Parkinson's disease may contribute to frailty and reduced healthspa…
Parkinson's patients on long-term levodopa face higher risks of dementia, falls, and death, echoing how other life-saving drugs later showed…
Qihuang needle therapy protocol for Parkinson's disease in 69 patients
Parkinson's Treatment Gets a New Brain Scan
This is a randomized controlled trial protocol for 69 Parkinson's disease patients, comparing Qihuang needle therapy to verum acupuncture, s…
Advanced brain scans reveal how a new needle therapy changes Parkinson's brain activity to help patients move better and feel less pain.
Blood miR-7-5p levels decrease more rapidly in Parkinson's disease patients than in healthy controls.
Blood Test Tracks Parkinson's Progress
This observational cohort study in the PPMI cohort found that blood miR-7-5p levels decreased more rapidly in people with Parkinson's diseas…
A new blood test tracks Parkinson's disease progress by measuring a molecule that drops faster in patients than healthy people.
Review explores PARP-1 and α-synuclein interactions in Parkinson's disease neuropathology
Could a protein switch drive the nerve damage seen in Parkinson's disease?
This narrative review synthesizes evidence on the interplay between PARP-1 activation and α-synuclein in Parkinson's disease, highlighting r…
An overactive protein switch in brain cells triggers the clumps and stress that drive nerve damage in Parkinson's disease.
REDDI pipeline improves balanced accuracy for classifying MCI, MS, Parkinson's, and ALS using MEG data.
Can a new computer tool help doctors spot brain diseases faster and more accurately?
This study developed a machine learning framework called REDDI that utilizes MEG resting-state data and Riemannian geometry for classifying …
A new computer tool helps doctors distinguish between hard-to-tell-apart brain diseases like Parkinson's and ALS with 13% better accuracy.
Sex-stratified multi-omic integration identifies specific molecular candidates and pathways in Parkinsons disease.
Why Men and Women Get Parkinson's Differently
This multi-omic integration study analyzed data from over 70,000 participants with Parkinsons disease and controls to identify sex-specific …
Men and women develop Parkinson's differently, with specific proteins driving the disease in each sex rather than a single cause for everyon…
Rhythmic auditory cueing and tDCS improve gait parameters in Parkinson's disease
Walking to the beat could help Parkinson's patients walk steadier
A clinical trial in 33 participants with Parkinson's disease and 32 healthy controls found that rhythmic auditory cueing increased cadence a…
Combining music and brain stimulation helps Parkinson's patients walk steadier and reduces their risk of falling without surgery.