Meta-analysis finds DBS improves REM sleep and reduces wakefulness in Parkinson's disease
The Unexpected Gift Deep Brain Stimulation Gives Parkinson's Patients at Night
A systematic review and meta-analysis of pre-post studies in patients with Parkinson's disease found deep brain stimulation (DBS) was associ…
A treatment known for easing Parkinson's tremors may also quietly help patients sleep better — especially during the dreaming stage of sleep…
Systematic review hypothesizes vitamin D3 and A combination may mitigate neurodegeneration
Could Two Common Vitamins Slow Alzheimer's and Parkinson's?
A systematic review proposes a hypothesis that combined vitamin D3 and vitamin A therapy may mitigate neurodegeneration in Alzheimer's and P…
A new theory suggests taking vitamins D and A together could protect brain cells by activating a unique switch to fight Alzheimer's and Park…
Peri-lead edema observed in 9.9% of Parkinson's patients undergoing deep brain stimulation surgery.
A Common Sleep Problem May Worsen Brain Surgery Recovery
This retrospective case-control study evaluated 121 Parkinson's disease patients undergoing deep brain stimulation. Symptomatic peri-lead ed…
For people with Parkinson’s, treating a sleep disorder before brain surgery might prevent a dangerous recovery setback.
China's rehabilitation needs for neurological disorders increased significantly from 1990 to 2021.
A Silent Wave of Disability is Rising. Here’s Who’s Most at Risk.
This cross-sectional analysis of data from China between 1990 and 2021 examined rehabilitation needs for ten neurological conditions, includ…
China faces a rising wave of neurological disability driven by aging, with stroke, Alzheimer's, and Parkinson's creating urgent long-term ca…
IMB model-based education improved medication adherence and self-management in Parkinson's disease patients at six months versus routine care.
IMB Education Improved Parkinson's Care Measures at Six Months
This randomized controlled trial evaluated an IMB model-based health education intervention versus routine health education in 70 patients w…
A special health education program helped Parkinson's patients manage their condition better and improve quality of life by six months.
Immersive virtual reality rehabilitation improved dynamic balance, motor function, and quality of life in Parkinson's disease patients.
Can virtual reality help people with Parkinson's move better and feel better?
This systematic review and meta-analysis of 13 studies involving individuals with Parkinson's disease compared fully immersive virtual reali…
Virtual reality therapy helps people with Parkinson's walk smoother and feel better, boosting their quality of life without serious side eff…
FDG-PET reveals dysregulated glucose metabolism as a common feature across late-onset neurodegenerative diseases with unique patterns.
FDG-PET scans show common brain glucose changes across several late-onset neurodegenerative diseases
This meta-analysis of 5,412 individuals with age-associated neurodegenerative diseases (A2ND) and 3,549 controls utilized FDG-PET to quantif…
FDG-PET scans reveal that dysregulated brain glucose metabolism is a shared feature across late-onset neurodegenerative diseases like Alzhei…
Rare variants in 44 dystonia genes show no major contribution to Parkinson's disease risk overall.
Rare genetic variants linked to dystonia do not appear to significantly increase Parkinson's disease risk overall.
This meta-analysis examined rare genetic variants in 5,315 Parkinson's disease patients and 36,902 controls from whole-genome sequencing dat…
Rare genetic variants linked to dystonia do not appear to significantly increase Parkinson's disease risk overall, according to a large gene…
Luteolin shows neuroprotective potential in preclinical models for Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis.
Luteolin shows potential benefits in early studies for neurodegenerative diseases
This review of preclinical studies and preliminary clinical observations suggests luteolin may reduce neuroinflammation and improve function…
Luteolin may help slow brain decline in Alzheimer's and Parkinson's by calming inflammation and boosting antioxidant defenses in early studi…
CSF alpha-synuclein seed amplification assay shows high intra-individual consistency in Parkinson's disease
Does a single brain scan truly predict Parkinson's disease years later?
An observational review of the PPMI cohort (n=1238) found serial CSF alpha-synuclein seed amplification assay (aSyn-SAA) results were highly…
A single brain scan predicting Parkinson's disease stays accurate for most patients, but results for healthy people without the disease can …
6-metabolite blood biomarkers aid differential diagnosis of Parkinson's disease versus healthy controls and other neurodegenerative conditions.
Can a simple blood test tell the difference between Parkinson's and other brain diseases?
This observational study assessed a 6-metabolite blood biomarker (6M-BB) profiled by 1H NMR for distinguishing Parkinson's disease (PD) from…
A simple blood test using six metabolites correctly identified Parkinson's disease in nearly 95% of cases while distinguishing it from other…
In Parkinson's disease, OFF predictability and clinical features explain more OFF impact variance than OFF time.
Study finds predictability of Parkinson's OFF episodes matters more than their duration
This observational review analyzed 1,252 OFF-only visits from 430 PPMI participants to identify correlates of OFF burden. Clinical features …
Parkinson's OFF episodes hurt more when they are unpredictable, not just when they are long, as new data shows predictability matters most f…