Connectomics-guided meta-learning framework decoded sleep spindles in 17 Parkinson's disease patients with DBS implants.
New method predicts sleep spindles in Parkinson's patients with high accuracy
This clinical study evaluated a connectomics-guided meta-learning framework in 17 patients with Parkinson's disease and bilateral deep brain…
A new system predicts sleep spindles in Parkinson's patients with 83% accuracy two seconds ahead, offering a path to target sleep disturbanc…
Systematic review examines neuroprotective plant extracts for Parkinson's disease mechanisms
Review explores how plant extracts might protect brain cells in Parkinson's disease
A systematic review summarized preclinical and clinical research on plant extracts with neuroprotective properties for Parkinson's disease. …
Plant extracts might protect brain cells in Parkinson's disease by reducing inflammation, stopping protein clumping, and helping nerve conne…
Systematic review finds wide variation in neurodegenerative disease prevalence among older Russian adults
How common are dementia and Parkinson's in Russia? The answer varies wildly.
A systematic review and meta-analysis of 20 community-based studies in Russia found dementia prevalence ranged from 0.5% to 81.6%, cognitive…
Dementia and Parkinson's rates in Russia swing wildly from 0.5% to over 80% depending on how doctors diagnose patients and which age groups …
Modeling suggests 30% Parkinson's progression reduction may lower 10-year milestone risks
Study models how slowing Parkinson's progression might reduce long-term risks
An observational cohort study of Parkinson's disease patients from the Oxford Parkinson's Disease Centre modeled a hypothetical 30% reductio…
Slowing Parkinson's disease progression by 30% could reduce long-term risks like dementia, falls, and death by up to 7.5% over 10 years, acc…
Greater cognitive variability in NSD Stage 2 predicts progression to advanced stages in observational study
Could a simple test of mental consistency help spot early Parkinson's disease?
An observational study of 934 participants from the Parkinson's Progression Markers Initiative found that greater intraindividual cognitive …
A simple mental consistency test can spot early Parkinson's disease signs before obvious symptoms appear, helping predict who will progress …
Meta-analysis finds depression associated with elevated Parkinson's disease risk
Could depression be an early sign of Parkinson's disease?
A meta-analysis of observational studies found depression was associated with approximately double the risk of developing Parkinson's diseas…
People with depression are about twice as likely to develop Parkinson's disease later, and brain scans in late-onset depression often show e…
Review suggests acupuncture may target cell death pathways in Parkinson's disease
Could acupuncture protect brain cells in Parkinson's disease?
A systematic review examined the role of programmed cell death in Parkinson's disease pathogenesis and the potential of acupuncture to targe…
Acupuncture may protect brain cells in Parkinson's disease by calming the inflammation and stress that trigger the cell death driving the co…
DBSgram framework demonstrates feasibility for biomarker-guided DBS programming in Parkinson's disease
Can brain signals and motion sensors help fine-tune Parkinson's treatment?
A cohort study of 18 Parkinson's disease patients with sensing-enabled DBS systems demonstrated technical feasibility of the DBSgram framewo…
A new system combines brain signals and wearable sensors to create visual guides that help doctors fine-tune Parkinson's deep brain stimulat…
Retrospective study finds 12.1% of PD/ET patients underwent DBS surgery at a tertiary center
Who gets brain surgery for Parkinson's? Insurance and neighborhood matter.
A retrospective cohort study of 3286 PD/ET patients at a single tertiary center found 12.1% underwent DBS surgery. Medi-Cal insurance and lo…
At one major center, patients with public insurance and low-income neighborhoods were more likely to get advanced brain surgery for Parkinso…
MRgFUS thalamotomy lesion connectivity patterns linked to tremor control in Parkinson's disease
What makes a Parkinson's tremor treatment last? Brain connections may hold the answer.
A retrospective observational study of 20 patients with tremor-dominant Parkinson's disease found durable tremor control after unilateral MR…
Parkinson's tremor relief lasts longer when brain lesions connect to movement areas rather than coordination centers, according to a new ana…
Cycling exercise may reduce urinary symptom progression in early Parkinson's disease pilot trial
Could regular cycling help with bladder problems in early Parkinson's?
An exploratory analysis of a pilot RCT in 30 patients with early Parkinson's disease found that 24 weeks of cycling exercise was associated …
Regular cycling may help slow worsening bladder symptoms in early Parkinson's, though this small study needs larger trials to confirm the be…
Telehealth CBT improves quality of life in veterans with Parkinson's disease and comorbid depression
Telehealth therapy improved quality of life for veterans with Parkinson's and depression
In a randomized controlled trial of 90 veterans with Parkinson's disease and primary depressive disorders, telehealth-delivered PD-informed …
Veterans with Parkinson's and depression who used video therapy saw better physical and mental quality of life compared to standard care.