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Patient Mode — summaries use plain language, avoiding clinical jargon.
Cardiology
RCT
Deferral of PCI non-inferior to routine PCI before TAVI in coronary artery disease patients
Study finds delaying heart artery procedure before valve replacement is as safe as doing it first
A randomised controlled trial of 466 patients undergoing TAVI with coronary artery disease in 12 Dutch hospitals found deferral of PCI was n…
Delaying heart artery procedures before valve replacement is just as safe as doing them first, with similar rates of death, heart attack, st…
Apr 14, 2026
Diabetes & Endocrinology
Cohort
TyG indices associated with coronary artery disease risk in first-time angiography patients
Your Blood Sugar and Fat Levels Together May Signal Heart Attack Risk
This retrospective cohort study evaluated 3,641 patients undergoing initial coronary angiography to assess the association between Triglycer…
Two routine blood test numbers, combined into one simple calculation, may give doctors a clearer early warning sign for heart disease than e…
Frontiers
Apr 14, 2026
Cardiology
Cohort
TyG index predicts complex CAD in young adults with aortic valve calcification
A Simple Blood Test Ratio Could Predict Heart Disease Risk Earlier
This cross-sectional study evaluated 260 young and middle-aged adults (aged 18–65 years) with aortic valve calcification to assess the assoc…
A straightforward blood calculation may help doctors spot dangerous heart disease earlier in younger adults who have a specific type of valv…
Frontiers
Apr 14, 2026
Primary Care & Family Medicine
RCT
Smartphone-based nursing intervention reduces pain after coronary artery bypass grafting
A Simple Phone Call Can Ease Heart Surgery Pain, Study Shows
A single-blind RCT of 80 adults undergoing elective CABG in Iran compared a nurse-led smartphone intervention with standard care. The interv…
Nurse-led smartphone check-ins after heart surgery reduced pain and helped patients feel more in control during recovery.
Apr 11, 2026
Cardiology
RCT
Edoxaban monotherapy reduces adverse events compared to dual therapy in patients with atrial fibrillation and coronary artery disease.
One Blood Thinner May Be Safer Than Two for Heart Rhythm Patients
This secondary analysis of a randomized clinical trial evaluated 1,040 patients with atrial fibrillation and stable coronary artery disease.…
Taking just one blood thinner instead of two cuts the risk of death, stroke, or bleeding for heart patients with irregular rhythms.
Apr 9, 2026
Genetics & Precision Medicine
Fine-mapping analysis identifies thousands of genetic variants contributing to coronary artery disease risk in over one million individuals.
Could thousands of tiny genetic changes be driving your heart disease risk?
This genome-wide association study (GWAS) fine-mapping analysis examined genetic contributions to coronary artery disease (CAD) risk in over…
Heart disease risk may be driven by thousands of tiny genetic changes, with about 34,000 variants collectively explaining nearly 4% of the r…
medRxiv
Apr 8, 2026
Cardiology
Meta-analysis
Network meta-analysis of 14 RCTs shows upfront plaque modification increases minimum stent area but does not reduce MACE or TLR in calcified coronary lesions.
New study finds risky plaque removal methods do not lower heart attack risk
This network meta-analysis of 14 randomized controlled trials involving 3,671 patients evaluated various plaque-modification strategies vers…
Special tools to break up hard heart plaque open arteries wider but do not lower the risk of heart attack or death compared to standard ball…
Apr 6, 2026
Radiology & Imaging
RCT
PCI with newer drug-eluting stents shows similar 10-year mortality to CABG for left main disease
For a serious heart artery blockage, do stents or bypass surgery offer better long-term survival?
In this phase 3 randomized trial of 1,184 patients with unprotected left main coronary artery stenosis, PCI with newer generation drug-eluti…
For serious heart blockages, a major 10-year study found stents and bypass surgery offer nearly identical survival rates, giving patients a …
Apr 6, 2026
Cardiology
RCT
Post-hoc analysis links lower systolic BP to higher cardiovascular risk in AF and stable CAD
Lower blood pressure linked to higher risk in AF patients with heart disease
A post-hoc analysis of the AFIRE trial (n=2135) found patients with atrial fibrillation and stable coronary artery disease who had baseline …
Patients with atrial fibrillation and low blood pressure face a 38% higher risk of heart attack, stroke, or death compared to those with hig…
Apr 6, 2026
Cardiology
Meta-analysis
Meta-analysis finds exercise training reduces hospitalization risk in coronary artery disease patients
Moderate exercise training reduces hospitalization risk for heart disease patients
A systematic review and meta-analysis of patients with coronary artery disease found that moderate-intensity continuous training (MICT) sign…
Moderate exercise training significantly reduces hospitalization risk for people with coronary artery disease, offering a safer path to bett…
Apr 6, 2026
Radiology & Imaging
Meta-analysis
Previously catheterised radial arteries show lower bypass graft patency in CABG patients
Should surgeons avoid using a previously catheterized artery for heart bypass?
A meta-analysis of 400 CABG patients found radial artery grafts from previously catheterised arms had 73.2% patency versus 83.9% for non-cat…
Using an artery for a heart catheterization weeks before bypass surgery may lower the graft's chance of staying open compared to a fresh art…
Apr 5, 2026
Cardiology
RCT
iFR-guided CABG improves mid-term graft patency versus angiography alone in multivessel disease
Can a simple test during heart surgery help grafts stay open longer?
A single-blinded RCT in patients with multivessel disease and intermediate stenoses found iFR-guided CABG significantly improved LIMA-to-LAD…
A simple pressure test during heart surgery keeps new blood vessel grafts open longer, with 80.5% staying clear versus 56.8% with standard i…
medRxiv
Apr 5, 2026