Narrative review explores multimodal approaches for autoimmune diseases including rheumatoid arthritis and Crohn's
Scarring From the Inside: How Your Immune System Can Turn Against Your Own Organs
This narrative review examines the integration of immune modulation, epigenetic reprogramming, and mechanobiological interventions for autoi…
Your immune system can cause permanent scarring inside organs like lungs and joints, driving autoimmune diseases such as rheumatoid arthriti…
Systematic review examines IL-35 and IL-39 roles in rheumatoid arthritis pathophysiology and therapeutic potential.
Two Hidden Signals May Explain Rheumatoid Arthritis Flares
This mini-review synthesizes available evidence regarding IL-35 and IL-39 in rheumatoid arthritis. The upstream regulatory architecture gove…
Two tiny immune signals fighting each other may hold the key to calming rheumatoid arthritis at its source.
Systematic review and meta-analysis finds CEUS comparable to MRI for synovitis detection
Can ultrasound find the same inflammation in joints as MRI without the high cost?
This systematic review and meta-analysis evaluated contrast-enhanced ultrasonography (CEUS) versus contrast-enhanced MRI for diagnosing syno…
Ultrasound with dye matches MRI accuracy for most joint inflammation, but falls short for rheumatoid arthritis cases.
Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis.
Your gut holds the key to your bone health.
This systematic review examines the role of gut microbiota dysbiosis in chronic kidney disease-mineral and bone disorder (CKD-MBD), rheumato…
Gut bacteria directly influence bone strength and kidney health, yet current treatments ignore the digestive system where the real problem s…
Systematic review examines lipid-immune crosstalk and dyslipidemia in rheumatoid arthritis patients.
The Hidden Link Between Arthritis Pain and Your Heart Health
This systematic review evaluated epidemiological evidence, clinical management strategies, and pathophysiological mechanisms regarding lipid…
Abnormal cholesterol is a direct driver of rheumatoid arthritis, explaining why people with RA face such a high risk of heart attack and str…
Implementation of cliexa-RA digital platform improved patient experience and time efficiency for 300 rheumatoid arthritis patients.
Tablets Replace Clipboards in a Rheumatoid Arthritis Clinic
This implementation case study evaluated the cliexa-RA digital platform in 300 rheumatoid arthritis patients at the Colorado Arthritis Cente…
A custom digital tool turned a slow paper workflow into a smooth tablet check-in that patients and doctors actually liked.
Interstitial lung disease reduces achievement of rheumatoid arthritis treatment goals over 24 months
Why Interstitial Lung Disease Blocks Rheumatoid Arthritis Goals
This retrospective cohort study examined 254 patients with newly diagnosed rheumatoid arthritis who underwent chest CT within one year of on…
Rheumatoid arthritis treatments often fail to reach pain-free goals when the disease also attacks the lungs, making standard care harder for…
Biological DMARDs show marginal patient-reported outcome benefits over conventional therapy in early rheumatoid arthritis
Early rheumatoid arthritis patients report similar symptom relief with different treatment approaches
This open-label randomized trial in 795 newly diagnosed, DMARD-naïve RA patients compared three biological DMARDs plus methotrexate against …
In early rheumatoid arthritis, patients reported similar pain relief and quality-of-life improvements whether they started with conventional…
Post-hoc analysis of RCTs and cohorts identifies predictors of remission in ACPA-positive early RA treated with abatacept plus methotrexate or methotrexate alone.
Early disease activity and response predict remission in ACPA-positive rheumatoid arthritis patients
This post-hoc analysis of randomized controlled trials and an observational cohort evaluated predictors of DAS28-CRP remission in ACPA-posit…
Only early disease activity and treatment response predict remission in ACPA-positive rheumatoid arthritis, while genetic markers and imagin…
Hand massage improves grip strength and function in early RA patients in pilot trial
Can hand massage improve grip strength and reduce pain in early rheumatoid arthritis?
A pilot randomized controlled trial of 30 female RA patients with low disease activity found that 10 hand massage sessions over 2 weeks sign…
Ten hand massage sessions boosted grip strength and lowered pain for women with early rheumatoid arthritis, while standard care alone showed…
Cross-sectional study finds association between autoimmune thyroiditis and rheumatoid arthritis
Could a common thyroid condition be linked to rheumatoid arthritis?
A cross-sectional analysis of NHANES data (n=5,715) and an external clinical cohort (n=196) found autoimmune thyroiditis was significantly a…
People with autoimmune thyroiditis are more likely to have rheumatoid arthritis, with uric acid levels playing a modest role in the connecti…
Phase 2 trial finds hydroxychloroquine does not prevent rheumatoid arthritis in at-risk individuals
Hydroxychloroquine did not prevent rheumatoid arthritis in at-risk individuals in trial
In a phase 2 randomized controlled trial of 144 individuals at risk for rheumatoid arthritis with elevated anti-CCP3 antibodies, 12 months o…
A new trial found that taking hydroxychloroquine for a year did not stop people at high risk for rheumatoid arthritis from developing the di…