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Rheumatology
Meta-analysis
Occupational inhalant exposures associated with increased rheumatoid arthritis risk in meta-analysis
Study links workplace dust and chemical exposure to higher rheumatoid arthritis risk
A systematic review and meta-analysis of 31 studies found significant associations between occupational inhalant exposures and increased rhe…
Breathing workplace dust and chemicals like silica and asbestos may raise your risk of developing rheumatoid arthritis, according to a revie…
Apr 7, 2026
Rheumatology
Meta-analysis
Rheumatoid arthritis is associated with a 58% higher risk of COPD compared to the general population.
Rheumatoid Arthritis Patients Face Higher Risk of Developing Chronic Lung Disease
This systematic review and meta-analysis evaluated 1,710,600 individuals to assess the prevalence and risk of chronic obstructive pulmonary …
People with rheumatoid arthritis face a significantly higher risk of developing chronic obstructive pulmonary disease compared to the genera…
NEJM
Apr 6, 2026
Rheumatology
Meta-analysis
FPGS Gene Variants Linked to Methotrexate Efficacy and Toxicity in Rheumatoid Arthritis
Could your genes explain why methotrexate works better for some people?
A meta-analysis of 2345 rheumatoid arthritis patients on methotrexate found FPGS polymorphisms rs10106 and rs1544105 were significantly asso…
Your genes might explain why methotrexate works better for some rheumatoid arthritis patients but also raises their risk of harmful side eff…
Apr 5, 2026
Dermatology
Meta-analysis
Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
Common arthritis and skin drugs linked to cholesterol changes, analysis finds
A systematic review and meta-analysis of 13 phase 2 and 3 RCTs involving 5,658 patients found treatment with oral JAK inhibitors (baricitini…
Common arthritis and skin drugs can raise both 'good' and 'bad' cholesterol levels, a review of nearly 4,000 patients shows.
Apr 4, 2026
Rheumatology
Cohort
Reduced anti-CXCR3 antibodies associated with systemic autoimmunity and atherosclerosis in cohort study
Study finds link between specific antibody levels and heart disease risk in autoimmune conditions
An observational cohort study of patients with rheumatoid arthritis, Sjogren disease, and controls found reduced anti-CXCR3 antibody levels …
Low levels of a specific antibody in early arthritis and joint pain are linked to higher heart disease risk and poorer medication responses.
medRxiv
Apr 4, 2026
Rheumatology
Immune signatures precede and accompany subclinical joint inflammation in ACPA-positive individuals at high risk for RA
Study finds immune changes in blood may signal early joint inflammation before rheumatoid arthritis
An observational study of ACPA-positive individuals at high risk for rheumatoid arthritis used single-cell transcriptomics and proteomics to…
Blood tests reveal specific immune cell changes that signal joint inflammation is starting before rheumatoid arthritis symptoms appear.
medRxiv
Apr 3, 2026
Rheumatology
RCT
Nurse counseling improves pain, fatigue, and function in rheumatoid arthritis patients in small RCT
Nurse counseling program helps rheumatoid arthritis patients manage pain and fatigue
A single-center RCT of 90 RA patients in Turkey found that education plus 3 months of telephone nursing counseling significantly improved pa…
A nursing counseling program helped rheumatoid arthritis patients feel less pain and fatigue while improving their ability to do daily activ…
Apr 3, 2026
Allergy & Immunology
Cohort
Review Links Gut Dysbiosis to Immune Dysfunction in Rheumatoid Arthritis
Could your gut health be linked to rheumatoid arthritis?
A review summarizes evidence linking gut dysbiosis to rheumatoid arthritis (RA). Specific microbial shifts are associated with impaired barr…
People with rheumatoid arthritis often have less diverse gut bacteria linked to immune attacks on joints and a leaky gut barrier.
Frontiers
Apr 3, 2026
Rheumatology
Cohort
Phenotype-based pain management in RA patients shows improved outcomes in retrospective cohort
Can matching pain type to treatment help people with rheumatoid arthritis?
A retrospective cohort study of 287 rheumatoid arthritis patients found that phenotype-specific interventions (pharmacological, psychologica…
Matching pain type to treatment helped 287 rheumatoid arthritis patients reduce inflammation, anxiety, and depression while improving sleep …
Frontiers
Apr 2, 2026
Allergy & Immunology
Meta-analysis
Elevated neutrophil-to-lymphocyte ratio correlates with higher mortality in rheumatoid arthritis
Higher blood cell ratio linked to increased mortality risk in rheumatoid arthritis patients
A meta-analysis of seven observational studies in patients with rheumatoid arthritis found elevated neutrophil-to-lymphocyte ratio (NLR) was…
A high blood cell ratio linked to severe inflammation raises the risk of death by 70% for people with rheumatoid arthritis.
Frontiers
Apr 2, 2026
Rheumatology
Meta-analysis
Meta-analysis finds nausea in 24% and abdominal pain in 20% of RA patients on methotrexate
How common is nausea and stomach pain for RA patients on methotrexate?
A systematic review and meta-analysis of 37 studies involving 19,986 adult RA patients on methotrexate found pooled prevalence rates of 24.3…
Nearly one in five rheumatoid arthritis patients taking methotrexate experience nausea or stomach pain, with about 8.5% stopping the drug du…
Apr 1, 2026
Rheumatology
Meta-analysis
Menopausal hormone therapy associated with modestly increased rheumatoid arthritis risk in meta-analysis
Menopausal hormone therapy linked to small increase in rheumatoid arthritis risk
A systematic review and meta-analysis of 5 studies with over 22 million person-years of follow-up in postmenopausal women found menopausal h…
Women using menopausal hormone therapy face a slightly higher risk of developing rheumatoid arthritis, particularly with long-term use.
Apr 1, 2026