Exercise reduces depression and anxiety symptoms across populations in meta-meta-analysis
Can exercise ease depression and anxiety? A massive review says yes.
A meta-meta-analysis of 63 studies (81 meta-analyses) involving 79,551 participants found exercise reduced depression (SMD=-0.61) and anxiet…
A massive review of nearly 80,000 people found exercise consistently reduces symptoms of both depression and anxiety across all ages.
Review organizes pharmacological strategies targeting gut-brain axis for neurological and psychiatric disorders
Could targeting gut health help treat brain disorders?
A systematic review summarizes mechanisms of microbiota–gut–brain axis dysfunction and organizes existing pharmacological strategies for con…
Treating brain disorders like Parkinson's and depression may involve targeting the gut-brain connection to reduce shared inflammation.
Antithrombotic agents may reduce symptoms in severe mental illness, but evidence is very low certainty
Blood-thinning drugs show possible benefit for severe mental illness symptoms
A systematic review and meta-analysis of 742 patients with severe mental illness found antithrombotic agents may reduce depressive symptoms …
Blood-thinning drugs might slightly ease severe mental illness symptoms, but experts warn the evidence is very uncertain and more research i…
Nutrition interventions may improve depression, anxiety, and diabetes distress in adults with diabetes
Can changing what you eat help ease the mental burden of diabetes?
A meta-analysis of 30 publications in adults with diabetes found nutrition interventions improved depression and anxiety scores and lowered …
Adjusting your diet to balance proteins, fats, and carbs can lower the specific distress of managing diabetes, though supplements helped eas…
Narrative review examines IBD as clinical model for chronic inflammation-depression connection
Review finds strong link between inflammatory bowel disease and depression
A narrative review using IBD as a clinical model found robust epidemiological evidence for a bidirectional association between IBD and depre…
Strong evidence shows inflammatory bowel disease and depression are linked bidirectionally, meaning each condition increases the risk of dev…
Review finds no single mental illness profile for terrorism among MENA youth
Review finds no single mental illness profile for terrorism among youth in MENA region
A narrative mini-review of youth mental health and religious radicalization in the Middle East and North Africa found no single 'mental illn…
No single mental illness profile predicts terrorism among youth in the Middle East, as everyday religious practice often protects against vi…
Exercise during adjuvant chemo reduces fatigue, depression in CRC patients
Can exercise help during colon cancer treatment? A review finds it may ease fatigue and depression.
A meta-analysis of 9 studies found exercise interventions during adjuvant chemotherapy for colorectal cancer significantly reduced fatigue (…
For colorectal cancer patients on chemotherapy, adding exercise to treatment significantly reduces crushing fatigue and lowers depression.
Cervical insufficiency associated with higher anxiety and depression scores in second-trimester pregnancy
Does a pregnancy complication make anxiety and depression more likely?
An observational study of 136 second-trimester pregnant women with cervical insufficiency and 117 healthy controls found significantly highe…
Women diagnosed with cervical insufficiency in their second trimester report significantly higher anxiety and depression than those with hea…
Livelihood Intervention Reduces Food Insecurity and Depression in HIV-Affected Kenyan Adolescents
Can improving livelihoods help HIV-affected teens feel better and safer?
A Kenyan RCT found that an agricultural livelihood intervention reduced food insecurity (OR: 0.45; p=0.04) and depressive symptoms (OR: 0.53…
An agricultural program in Kenya helped HIV-affected teens feel safer by reducing food insecurity, depression, anxiety, and intimate partner…
Ketamine in Orthopedic Trauma: Potential to Reduce Pain and Opioid Use
Could Ketamine Be the Key to Easing Pain and Healing Minds After Surgery?
This Phase 4 trial investigates ketamine's efficacy in reducing postoperative pain and opioid use in orthopedic trauma patients. Primary out…
A new trial tests if giving ketamine during orthopedic surgery reduces pain, opioid needs, and symptoms of depression and PTSD compared to s…
CFT Improves Depression and Emotional Eating in Severe Obesity: RCT Results
Can Kindness to Yourself Help Tackle Obesity and Depression?
In a single-centre RCT with 91 participants, group-based Compassion Focused Therapy (CFT) significantly improved self-compassion, mood, and …
A 10-session therapy teaching self-compassion helped people with severe obesity feel less shame, eat healthier, and improve their mood for m…