Meta-analysis on psychological interventions and early psychosis care for depression and psychosis
Psychological interventions cut major depression risk by 43% after treatment
This meta-analysis synthesizes evidence on psychological interventions for subclinical depression and early intervention for first-episode p…
Early psychological help for subclinical symptoms lowers major depression risk by 43% after treatment and 33% a year later, a meta-analysis …
Observational cohort links symptom severity subgroups to poorer functioning and brain volume in psychosis and depression risk.
Severe Mental Symptoms Share Hidden Common Cause
This observational cohort study stratified 749 participants into transdiagnostic symptom severity subgroups. Symptom severity was associated…
This could explain why different mental illnesses feel so similar in early stages.
Review of P-NQLS psychometric validation in U.S. parents of children aged 6-18 years.
Parents See Kids’ Mental Health Differently Than Doctors Do
This narrative review summarizes a psychometric validation study of the Parent-report Nationwide Quality of Life Scale (P-NQLS) in 2,251 U.S…
Six-year-old Maya used to laugh at everything.
Bayesian network meta-analysis of exercise interventions for depression and anxiety in cancer survivors
Mind-Body Exercises Top New Depression and Anxiety Relief List
This Bayesian network meta-analysis evaluated different exercise interventions versus non-exercise controls for depression and anxiety in 7,…
Slow, gentle movement like Tai Chi and Pilates now ranks highest for easing depression and anxiety in cancer survivors, offering a practical…
Elobixibat improved constipation in schizophrenia or depression patients during postmarketing surveillance in Japan.
New Hope for Constipation in Mental Health Patients
This postmarketing cohort study evaluated elobixibat in 105 patients with schizophrenia and 129 with depression in Japan. Defecation frequen…
A new drug helps millions with mental health conditions overcome severe constipation caused by their mood-stabilizing medications.
Systematic review and meta-analysis on depression and anxiety prevalence in liver cirrhosis
More Than Half of Cirrhosis Patients Face Anxiety, New Global Study Reveals
This meta-analysis synthesized data from 23 studies including 979,113 patients with liver cirrhosis to estimate the prevalence of depression…
This massive global review proves that mental health struggles are a hidden, widespread crisis for people living with liver disease.
Case-control study links impaired decision-making tasks to suicide attempts in depressed patients.
Can't weigh risks and rewards? Suicide attempters show different decision-making patterns
This case-control study assessed 132 depressed patients with suicide attempts, patient controls, and healthy controls using clinical decisio…
People who attempted suicide weigh risks differently, showing less fear of loss and more impulsive errors that link directly to higher suici…
Narrative review explores psychobiotics and lifestyle changes for chronic constipation-depression comorbidity
Your Gut and Your Mood Are Talking — Here's What They're Saying
This narrative review examines potential strategies for managing chronic constipation and depression comorbidity, including psychobiotics, f…
Chronic constipation and depression often share a common cause: gut bacteria imbalances that disrupt the signals between your digestive syst…
Meta-analysis links diabetic retinopathy with anxiety and depression in over 383,000 patients.
Diabetes Eye Disease and Depression Feed Each Other — and Doctors Are Just Catching On
This meta-analysis synthesizes observational data from 383,195 patients with diabetic retinopathy and/or diabetes mellitus to evaluate the a…
Diabetic eye disease and depression trap patients in a two-way cycle where each condition significantly raises the risk of the other.
Meta-analysis finds machine learning models predict depression in diabetes with AUC 0.822
Can computer models predict diabetes depression risk better than usual guesses?
This systematic review and meta-analysis evaluated machine learning-based risk predictive models for depression in patients with diabetes me…
Computer models predict diabetes depression risk well in tests, but experts warn they are not ready for doctors to use on patients yet.
Pilot RCT in veterans with depression finds no benefit from immediate PGx testing.
Your Genes Could Predict Which Antidepressant Actually Works for You
A pilot randomized clinical trial in 60 veterans with depression compared immediate vs. delayed PGx test results over 2.8 months. No signifi…
A DNA-based approach to choosing antidepressants may work better when doctors first identify patients most likely to have a gene-drug mismat…
Meta-analysis shows psychotherapy effect sizes vary by baseline depression severity compared to control conditions.
Depression Treatment Works Best For The Most Severe Cases
This meta-analysis evaluated 47,315 patients with depression to assess how baseline severity influences treatment response. Psychotherapies …
Depression therapy works best for the most severe cases, with response rates improving as symptoms worsen, according to a large review of 38…