Systematic review and meta-analysis of 3D cardiac simulations for congenital heart disease surgery
3D heart models help surgeons plan better operations for children with heart defects
This systematic review and meta-analysis synthesized evidence on patient-centred 3D cardiac simulations for congenital heart disease surgery…
Using 3D heart models changed surgical plans more often and shortened hospital stays for patients having heart surgery.
Breast arterial calcification linked to increased cardiovascular mortality risk
Calcified breast arteries linked to higher risk of heart disease and death
This meta-analysis examined associations between breast arterial calcification and cardiovascular outcomes. The authors observed that the pr…
A large analysis shows breast arterial calcification is associated with higher risks of heart failure, stroke, and death in women.
Systematic review and meta-analysis links pediatric cerebral AVMs with congenital heart defects and outlines prognostic factors
Brain and heart defects often appear together in children, raising new questions for care
This systematic review and meta-analysis examines the association between cerebral arteriovenous malformations (AVMs) and congenital heart d…
A large review found that brain and heart defects frequently occur together in kids, changing how doctors should watch for complications.
Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
Vaccination Before Infection Cuts Heart and Stroke Risks in COVID Patients
This systematic review and meta-analysis examined the association between pre-infection COVID-19 vaccination and cardiovascular outcomes in …
Pre-infection COVID-19 vaccination significantly lowers risks of heart attacks, strokes, and other cardiovascular events in infected individ…
Systematic review finds CRT plus optimized medical therapy is highly cost-effective for symptomatic heart failure patients
Heart Failure Therapy Costs Vary by Device Type
A systematic review evaluated the cost-effectiveness of cardiac resynchronization therapy compared to optimized medical therapy in patients …
A review of eighteen studies suggests adding cardiac resynchronization therapy to standard care is highly cost-effective for patients with h…
Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
Routine valve closure did not significantly reduce stroke risk in heart surgery patients
In a randomized trial involving 2118 patients undergoing valve repair or replacement, surgical left atrial appendage occlusion failed to low…
A major surgery trial found that closing a heart chamber did not lower stroke risk compared to standard care for patients getting valve repa…
Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
Four Chinese medicines show promise for heart failure after heart attack
This network meta-analysis evaluated oral Chinese patent medicines combined with conventional treatment in patients with myocardial infarcti…
A network meta-analysis of 42 trials found four oral Chinese patent medicines improved outcomes when added to standard heart failure treatme…
Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months
Simplified care plan shows no overall benefit for heart failure patients
This multicenter randomized clinical trial enrolled 982 patients with acute heart failure. The study evaluated a simplified transitional car…
A new trial found that a simplified discharge plan did not improve medication adherence or symptoms for most heart failure patients, though …
M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation
Heart Valve Repair Improves Symptoms in Heart Failure Patients
This RCT subgroup analysis found that mitral transcatheter edge-to-edge repair (M-TEER) reduced the risk of cardiovascular death or heart fa…
A study found that mitral valve repair with MitraClip improved symptoms and reduced hospitalizations in heart failure patients with mitral r…
Meta-analysis suggests high BMI causally increases vascular-related dementia risk via blood pressure mediation
Higher body weight linked to increased risk of vascular dementia
This Mendelian randomization meta-analysis evaluates the causal link between high body mass index and vascular-related dementia. The analysi…
A large genetic study shows that a higher body mass index (BMI) raises the risk of vascular-related dementia. High blood pressure plays a ke…
Meta-analysis links influenza vaccination to lower mortality in acute heart failure
Flu Shot Linked to Lower Death Risk in Heart Failure Patients
This meta-analysis of 5 observational studies found that influenza vaccination was associated with reduced 1-year and 90-day mortality in pa…
A review of five studies found that flu vaccination was associated with about 11% lower risk of death within one year in patients with acute…
Narrative review explores strategic collaborations to expand interventional cardiology access in sub-Saharan Africa
Strategic partnerships help bring heart care services to people in sub-Saharan Africa
This narrative review examines how strategic collaborations can increase equitable access to interventional cardiology in sub-Saharan Africa…
This review looks at how working together can improve heart care in sub-Saharan Africa. It aims to close the gap for patients with coronary …
Questions about Heart Failure
Are SGLT2 inhibitors effective for treating heart failure with mildly reduced ejection fraction?
Yes, SGLT2 inhibitors are effective for treating heart failure with mildly reduced ejection fraction, reducing heart failure hospitalizations and improving outcomes.
Full answer →Does finerenone help patients with heart failure with mildly reduced ejection fraction?
Yes, finerenone reduces cardiovascular death and worsening heart failure events in patients with heart failure with mildly reduced ejection fraction, based on a network meta-analysis and the FINEARTS-HF trial.
Full answer →Can erythropoiesis-stimulating agents help adults with chronic heart failure and anaemia?
Erythropoiesis-stimulating agents (ESAs) reduce total heart failure hospitalizations and improve exercise tolerance in adults with chronic heart failure and anaemia, but do not lower mortality risk.
Full answer →Do alternative loop diuretics reduce hospitalizations for patients with chronic heart failure?
No, alternative loop diuretics (torsemide, azosemide, piretanide) do not reduce hospitalizations compared to furosemide in chronic heart failure, based on a systematic review of 23 trials.
Full answer →What are the main themes in coping experiences for chronic heart failure patients and caregivers?
Coping experiences for CHF patients and caregivers center on differing views of illness, emotional exhaustion, strained relationships, and a need for support to find new meaning.
Full answer →Does taking Qishen Yiqi dropping pills plus Western medicine improve chronic heart failure efficacy?
A 2024 trial found that adding Qishen Yiqi dropping pills to standard Western medicine improved clinical effectiveness and heart function in chronic heart failure patients.
Full answer →Does having higher levels of EPA in my blood increase my risk of ischemic heart disease?
Higher EPA levels may slightly increase ischemic heart disease risk, according to genetic studies, but the evidence is not definitive.
Full answer →What side effects or benefits did levosimendan show for patients with acute heart failure?
Levosimendan improves symptoms and heart function in acute heart failure, but can cause hypotension and tachycardia; benefits may vary by BMI.
Full answer →All Heart Failure Articles
- Breast arterial calcification linked to increased cardiovascular mortality risk
- Systematic review and meta-analysis of 3D cardiac simulations for congenital heart disease surgery
- Systematic review and meta-analysis links pediatric cerebral AVMs with congenital heart defects and outlines prognostic factors
- Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
- Systematic review finds CRT plus optimized medical therapy is highly cost-effective for symptomatic heart failure patients
- Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
- Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
- Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months
- M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation
- Meta-analysis suggests high BMI causally increases vascular-related dementia risk via blood pressure mediation
- Narrative review explores strategic collaborations to expand interventional cardiology access in sub-Saharan Africa
- Meta-analysis links influenza vaccination to lower mortality in acute heart failure
- Meta-analysis shows SGLT2 inhibitors reduce all-cause mortality in heart failure patients
- Systematic review and meta-analysis finds no mortality benefit for alternative loop diuretics in chronic heart failure
- SGLT-2 inhibitors reduce heart failure hospitalization and stroke in patients with acute coronary syndrome
- Systematic review and meta-analysis reports 36.6% cognitive impairment prevalence in coronary heart disease patients
- Higher LDH levels linked to increased heart failure events in HFrEF patients
- Meta-analysis links elevated GDF-15 to mortality in acute heart failure
- CABG versus PCI in high-risk coronary revascularisation patients shows mixed outcomes over 5 years
- Transcatheter valve replacement improves outcomes in severe tricuspid regurgitation
- Systematic review and meta-analysis on face-directed fan therapy for dyspnea in advanced disease
- Qiliqiangxin reduces cardiovascular events in heart failure with reduced ejection fraction across LVEF subgroups
- Systematic review and meta-analysis of erythropoiesis-stimulating agents in chronic heart failure and anaemia
- Meta-analysis and cohort study suggest association between SGLT2 inhibitors and reduced arrhythmia recurrence
- Network meta-analysis suggests mind-body exercises improve quality of life and function in chronic heart failure patients
- Nurse and social worker telecare team intervention improved quality of life in high-risk patients with COPD, heart failure, or interstitial lung disease
- Beta-blockers show no mortality benefit in MI patients with preserved ejection fraction
- Sex differences in genetic correlation between ischaemic heart disease and depression found in 1.14 million European ancestry individuals
- Network meta-analysis of oral Chinese patent medicines for coronary heart disease with diabetes
- Machine learning model using routine clinical indicators predicts coronary heart disease risk
- Deep learning model screens for transthyretin amyloid cardiomyopathy using ECG images
- Mendelian randomization links higher plasma EPA to increased ischemic heart disease odds
- NICE-Support programme improves frailty and quality of life in stable heart failure patients
- Systematic review and meta-analysis shows remote monitoring reduces mortality and hospitalizations in heart failure
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- Chagas disease associated with higher in-hospital mortality in adults hospitalized with heart failure
- Systematic Review and Meta-Analysis Finds Palliative Care Improves Quality of Life in Advanced Heart Failure
- Narrative review summarizes Systemic Immune-Inflammation Index thresholds and limitations in coronary heart disease management
- GenMetS polygenic score association with cardiometabolic risk in Asian populations
- Randomized trial of anakinra in heart failure shows increased IL-1Ra levels versus placebo over 24 weeks
- Higher systemic immune-inflammation index linked to increased mortality risk in hospitalized heart failure patients
- Review Links Central Adiposity to Higher Infective Endocarditis Risk in UK Biobank
- Deep Learning Model Outperforms Guidelines for Heart Failure Prognosis
- Telemedicine applications in general practice show positive clinical outcomes for chronic diseases
- Jordan guideline review highlights SGLT2 inhibitor access barriers for heart failure patients
- Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
- Multi-ancestry meta-analysis identifies X-chromosome loci for heart failure phenotypes
- Registry study links ARNI therapy groups to divergent mortality and hospitalization risks in HFrEF patients
- PSI-QPI metrics improved prediction of TTN-TV disease penetrance and expressivity in cardiomyopathy patients
- Hospital stay and mortality vary by pandemic wave and vaccination status in severe COVID-19
- Retrospective cohort study links congenital heart surgery with CPB to early postoperative cerebral desaturation events in infants
- Diabetes Prevalence and Clinical Correlates in Hospitalized Heart Failure Patients in China
- Discharge to healthcare facilities increased 6-month readmission risk in Chinese heart failure patients compared to home discharge
- Higher RAR linked to increased in-hospital mortality in infants with congenital heart disease
- CRRT after heart transplantation linked to preoperative hemoglobin and VIS score in cohort study
- Single-center review links CPAP compliance to better survival in LVAD patients with OSA
- TyG-NLR combined index associated with all-cause mortality in heart failure patients
- Systematic literature review examines machine learning applications in congenital heart disease across 432 references
- Review of ginsenoside CK shows potential antiplatelet, anti-inflammatory, and cardioprotective effects in cardiovascular disease models
- Individual participant data meta-analysis shows exercise-based cardiac rehabilitation reduces hospitalization, not mortality in coronary heart disease
- Non-traditional lipid indices associate with coronary heart disease risk in MASLD and type 2 diabetes patients
- Review Examines IL-32 Role in Cardiovascular Diseases and Atherosclerosis
- Narrative review summarizes evidence on exercise benefits for cardiovascular disease and mortality risk reduction
- Narrative review synthesizes evidence on myocardial strain imaging for pediatric congenital heart disease management
- Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
- Meta-analysis of 13 trials finds SGLT2 inhibitors reduce heart failure hospitalization in myocardial infarction
- Beta-blockers show no benefit in preserved LVEF post-MI, but may help mildly reduced LVEF
- Review proposes pragmatic framework for pediatric heart failure management addressing myocarditis and MIS-C
- Retrospective observational study of 122 heart failure patients at 2,800 meters altitude in Quito
- Observational Cohort Study Links Dynamic Cardiac Shape to Cardiometabolic Disease Risk in UK Biobank
- Modeling Study Estimates Polygenic Embryo Screening Risk Reductions in IVF Patients and Egg Donors
- Standard diuretic therapy within GDMT yielded comparable outcomes to pleural drainage in elderly acute heart failure with moderate pleural effusion
- Narrative review on ultra-processed foods and cardiovascular disease mechanisms
- Review of heart failure medications and microbiome insights for individualized treatment strategies
- Obesity-metabolic indices associated with heart failure in coronary artery disease patients
- Blood levels of Mn, Fe, Zn, Cd, and Cr associated with HF status in Saudi outpatients
- Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts
- SMART-HF guided workflow improved PAD control in adults with heart failure and implanted sensors
- GLP-1 receptor agonists associated with lower mortality in HFrEF on GDMT
- Review links periodontitis to higher cardiovascular risk but notes causal inference is unproven
- Pilot retrospective case control study of congenital heart disease in maternal-infant dyads
- Narrative review explores metformin and trimetazidine in cardiovascular conditions
- IL-17A inhibition improves skin lesions and early atherosclerosis markers in psoriasis vulgaris patients
- In PH-LHF patients, arrhythmia types predict mortality and rehospitalization, with AT prevalence at 42.2%
- Predictive model for acute heart failure in STEMI patients after PCI shows high accuracy
- Home-based cardiac rehab yields greater mental health and HRQoL gains in heart failure patients with elevated depression
- Anemia prevalence is 56.4% in heart failure patients, linked to worse clinical profiles
- SGLT2i use linked to lower adherence and QOL in HF patients in cross-sectional MTAC study
- Systematic review of multimodal machine learning models for heart failure classification and prognosis prediction
- Axillary IABP support enables ambulation in most heart failure patients with low complication rates
- One-year post-CABG diastolic function worsens despite preserved ejection fraction in ischemic heart disease patients
- Systematic review and meta-analysis of insomnia prevalence and risk factors in patients with coronary heart disease
- Retrospective study of levosimendan use in acute heart failure patients across Jiangxi Province hospitals
- Semaglutide dose linked to lower mortality and cardiovascular risk in patients with baseline CVD
- Disability benefit take-up varied by cause of death and geography in England and Wales
- Carotid plaque measures predict coronary heart disease in CKD patients
- Cardiac procedures in neonates with congenital heart disease alter spatial cardiac motion patterns compared to healthy controls
- Qishen Yiqi dropping pills plus conventional Western medicine improved efficacy in chronic heart failure patients
- Adenosine and other interventions show variable success in adult paroxysmal supraventricular tachycardia patients
- Hospital at home reduces length of stay and 30-day readmissions in patients with heart, airway, or respiratory conditions
- Plasma proteins linked to HCM severity identified in MYBPC3 carriers and UK Biobank
- Meta-analysis shows altered muscle morphology and metabolism in heart failure patients versus healthy controls
- Telemedicine-based exercise cardiac rehabilitation shows comparable effects to center-based programs for coronary heart disease patients
- Cardiac resynchronization therapy improves ventricular function and symptoms in adult congenital heart disease patients with heart failure
- Qiliqiangxin capsule adjunctive therapy reduces cardiovascular death and hospitalization in patients with heart failure with reduced ejection fraction
- CHIP mutations increase cardiovascular risk and mortality in older adults independent of traditional factors
- Computational platform expands genetic screening scope in high-consanguinity Gulf populations
- Frailty shows strong positive association with depression in older adults with coronary heart disease
- Higher Dietary Inflammatory Index Scores Associated with Increased MACE in CHD Patients
- Remote monitoring chatbot increased GDMT target dose achievement in recently discharged HFrEF patients compared to standard care
- Oral semaglutide reduces composite heart failure outcomes in patients with type 2 diabetes and heart failure history
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Type 2 Diabetes and Heart Failure Risk Reduction
- Mendelian randomization meta-analysis links genetically predicted obesity traits to increased heart failure risk
- Apixaban alters hemostatic biomarkers in children with heart disease compared to standard care
- Food insecurity associated with poorer health status in children with congenital heart disease
- Brain age gap shows neurodevelopmental delays in preterm neonates and worsens after CHD surgery
- Protocol outlines non-invasive skeletal muscle assessment in adolescents with single ventricle heart disease versus matched controls
- Maternal voice intervention effects on sleep in children with congenital heart disease undergoing open-heart surgery remain unreported in this protocol
- FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk and Improve Glycemic Control in Adults with Type 2 Diabetes
- FDA Approves Dapagliflozin for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin for Reducing Heart Failure Hospitalization Risk and Improving Glycemic Control in Adults with Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Type 2 Diabetes and Heart Failure Risk Reduction
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk in Adults with Type 2 Diabetes
- Meta-analysis finds SGLT2 inhibitors reduce mortality and hospitalization in older heart failure patients
- Observational EHR study suggests GLP-1 RA may have lower risk than SGLT2i for HF outcomes
- Conduction system pacing showed inferior outcomes compared to biventricular pacing in adults with heart failure and left bundle-branch block
- Left bundle-branch pacing reduced death or heart failure hospitalization compared with biventricular pacing in heart failure with left bundle-branch block
- Elevated circulating Lp(a) levels associated with increased heart failure incidence in 400,631 participants
- Meta-analysis finds IABP may improve 60-day outcomes in advanced heart failure-related cardiogenic shock
- Exercise training improves multiple outcomes in frail older adults with heart failure
- Standardized feeding pathway improves documentation and alert adherence in postoperative CHD infants
- AI approaches show potential for mapping brain-heart network interactions in neurocardiology
- Intensive medical treatment failed to reduce major adverse cardiovascular events in women with suspected ANOCA/INOCA over 2.5 years
- Planned HF hospitalization program linked to lower costs, shorter stays in small retrospective study
- Beta-blocker discontinuation noninferior to continuation in stable post-MI patients without heart failure
- HIIT improves exercise capacity in cardiovascular rehabilitation for CAD, HF, and atrial fibrillation
- Tracheobronchial anomalies associated with congenital heart disease in retrospective CT cohort
- Heart disease and cancer death rates studied in US adults aged 45-64 from 1999 to 2018
- Observational report finds decline in emergency visits for heart attack, stroke, hyperglycemic crisis during early COVID-19
- COVID-19 was the third leading cause of death in the United States in 2021
- Report examines racial and ethnic disparities in diagnosed heart disease and diabetes among US adults
- Afterload-adjusted strain associated with outcomes in mixed aortic valve disease
- Deep learning model predicts left atrial imaging from ECG, improves AF and HF risk stratification
- Covariate adjustment method for hierarchical outcomes improves statistical power in win ratio analyses
- ECG parameter P0PV1 identifies CRT-D benefit and harm in non-LBBB heart failure patients
- Furosemide plus hypertonic saline linked to lower biomarker increases after saline load in ADHF
- RAS Inhibitors After TAVR Associated With Reduced Mortality in Meta-Analysis of 36,000 Patients
- Bariatric surgery associated with lower cardiovascular risks than GLP-1RA therapy in adults with obesity
- Systematic review outlines role of mitochondrial DNA mutations in heart failure pathogenesis
- GLP-1 receptor agonists reduce new-onset heart failure risk in patients with diabetes or obesity
- Black participants less represented in US heart failure registries than in clinical trials
- TTE-guided leadless pacemaker implantation shows feasibility and comparable duration to fluoroscopy in small cohort
- Autologous pericardial annuloplasty linked to lower TR recurrence in rheumatic heart disease
- Retrospective study of semaglutide in 17 patients with type 2 diabetes and end-stage renal disease
- Qualitative synthesis identifies four themes in dyadic coping experiences for chronic heart failure
- FDA Approves Xarelto (rivaroxaban) for Thromboprophylaxis in Pediatric Patients After Fontan Procedure
- Phase 4 study evaluates nitroglycerin's effects on stroke volume in 21 AHF patients
- Phase 2a trial of DFV890 and MAS825 for inflammation in CHD/CHIP patients completes with 31 participants
- GBM model predicts postoperative delirium in elderly CHD patients with 0.856 AUC
- Immediate revascularization tied to higher 1-year risk in STEMI with multivessel disease and heart failure
- Web Portal Use in Type 2 Diabetes: Uptake Driven by Intentions, Not Frequency