Corticosteroid therapy associated with greater weight loss and poorer appetite in advanced pancreatic cancer
Corticosteroid therapy linked to more weight loss in advanced pancreatic cancer patients
A post hoc analysis of the MISTRAL trial in 244 patients with advanced pancreatic cancer found corticosteroid therapy was associated with gr…
Corticosteroid therapy linked to more weight loss in advanced pancreatic cancer patients, who also reported less appetite and lower BMI duri…
Meta-analysis: Preoperative calcitonin predicts lateral cervical lymph node metastasis in medullary thyroid carcinoma
Can a simple blood test help surgeons plan thyroid cancer operations?
A meta-analysis of 8 studies (951 patients) with medullary thyroid carcinoma found preoperative serum calcitonin demonstrated good diagnosti…
A simple blood test measuring calcitonin levels can accurately predict if medullary thyroid cancer has spread to neck lymph nodes before sur…
Periodontal disease associated with increased oral cancer odds in meta-analysis of case-control studies
Could gum disease raise your risk of oral cancer? A new review suggests a link
A systematic review and meta-analysis of 18 case-control studies including 31,504 adults found periodontal disease was associated with incre…
Severe gum disease is linked to a 2.3 times higher risk of oral cancer in adults, signaling a deep connection between oral and overall healt…
Extended goal-directed fluid therapy shows no benefit for complications after esophagectomy in single-center trial
Does personalized fluid therapy after esophageal cancer surgery reduce complications?
A single-center, single-blind RCT of 100 patients undergoing esophagectomy found that extended, individualized goal-directed fluid therapy d…
Personalized fluid therapy after esophageal cancer surgery did not reduce complications, despite higher fluid intake and medication use in p…
Meta-analysis reports 53% 2-year overall survival after haploidentical HSCT in older adults
Study reviews survival rates for older adults after haploidentical stem cell transplants
A systematic review and meta-analysis of 16 studies including 1,268 adults aged ≥60 years with hematologic malignancies found pooled 2-year …
For older adults with blood cancers, haploidentical stem cell transplants show a two-year survival rate of 53%, though results vary widely b…
Augmented reality game shows no significant effect on persistent opioid use after pediatric surgery
Augmented reality game shows no clear advantage over regular game for pediatric surgery pain
A pilot RCT of 66 opioid-naïve pediatric patients undergoing major surgery found no statistically significant difference in persistent opioi…
Playing an augmented reality scavenger hunt after major surgery did not lower opioid use or pain levels in children compared to a regular ga…
ERAS-guided refined nursing associated with earlier mobilization after lung cancer surgery in retrospective cohort
Could a new nursing approach help lung cancer surgery patients get moving faster?
A retrospective cohort study of 136 patients undergoing radical lung cancer surgery found ERAS-guided refined nursing was associated with si…
A new nursing approach helps lung cancer surgery patients get out of bed and walk sooner, perform better on mobility tests, and recover fast…
Adjuvant NSAIDs associated with improved DFS in resected PIK3CA-mutated colorectal cancer
NSAID therapy after surgery may help prevent colorectal cancer recurrence in some patients
A meta-analysis of 789 patients with resected PIK3CA-mutated colorectal cancer found adjuvant NSAID therapy (aspirin or COX-2 inhibitors) wa…
Taking anti-inflammatory drugs like aspirin after colorectal cancer surgery may lower the risk of the cancer returning in patients with a sp…
Review summarizes molecular pathways and treatment options for Adult T-cell leukemia/lymphoma
What helps patients with a rare, aggressive blood cancer?
A systematic review summarizes the molecular pathogenesis and treatment landscape for Adult T-cell leukemia/lymphoma (ATLL).
For patients with rare, aggressive Adult T-cell leukemia/lymphoma, a drug called mogamulizumab shows promise when standard treatments fail.
Phase 3 trial of pembrolizumab plus chemo for advanced biliary tract carcinoma posts results
Can adding pembrolizumab to standard chemo help people with advanced bile duct cancer?
A phase 3 randomized controlled trial in 1,069 participants with advanced biliary tract carcinoma compared first-line pembrolizumab plus…
A large trial of adding immunotherapy to standard chemo for advanced bile duct cancer is complete, but the results showing if patients live …
Survey finds 67% of U.S. adults aged 50-75 met colorectal cancer screening recommendations
Survey finds about two-thirds of eligible U.S. adults are up to date on colon cancer screening
A 2018 observational survey of U.S. adults aged 50-75 found 67.0% met USPSTF colorectal cancer screening recommendations, and 60.6% reported…
About two-thirds of eligible U.S. adults aged 50 to 75 were up to date on colon cancer screening, yet a gap remains for many people.
Survey examines colonoscopy utilization among U.S. adults aged 50-75 without colorectal cancer history
Survey examines colonoscopy use among U.S. adults recommended for screening
An observational survey report assessed colonoscopy utilization in the past 10 years among U.S.
A new survey tracks how many U.S. adults aged 50 to 75 without colorectal cancer had a colonoscopy for screening in the last decade.
Questions about Cancer
How does receptor discordance in metastatic breast cancer impact overall survival rates?
Receptor discordance in metastatic breast cancer is linked to worse overall survival, especially when hormone receptors are lost.
Full answer →What does a pilot study say about deep longitudinal profiling for metastatic cancer patients?
The provided sources do not contain any pilot study on deep longitudinal profiling for metastatic cancer patients.
Full answer →Does having different receptors in metastatic breast cancer lesions affect how long I live?
Yes, different receptor types in metastatic breast cancer lesions are linked to different survival times, with hormone receptor-positive subtypes generally having longer survival than HER2-positive or triple-negative subtypes.
Full answer →What immune checkpoint inhibitor is best for survival in metastatic cervical cancer?
Pembrolizumab plus chemotherapy is the best-supported immune checkpoint inhibitor for improving overall survival in metastatic cervical cancer, especially in PD-L1 positive patients.
Full answer →Does the neutrophil-to-lymphocyte ratio predict progression-free survival in metastatic cervical cancer patients?
A high neutrophil-to-lymphocyte ratio (NLR) before treatment predicts shorter progression-free survival in metastatic cervical cancer patients receiving immunotherapy, while a low ratio suggests better outcomes.
Full answer →How does the neutrophil-to-lymphocyte ratio predict survival in metastatic cervical cancer treated with immune therapy?
A lower neutrophil-to-lymphocyte ratio (NLR) before starting immune therapy predicts longer survival and better response rates in metastatic cervical cancer, while a higher ratio signals a worse outlook.
Full answer →What evidence exists for liver cancer alongside lung, breast, and kidney cancer?
Research shows liver cancer detection using liquid biopsies has high accuracy similar to lung, breast, and kidney cancers, while survival rates for liver cancer have improved significantly in recent years.
Full answer →Can machine learning with cfDNA help detect liver cancer at different stages?
Yes, machine learning with cfDNA can detect liver cancer at various stages, with sensitivities ranging from 44% for stage I to 99% for stage III and high specificity.
Full answer →