Population study links PALB2 variants to increased cancer risk and mortality in two large cohorts
Large study finds PALB2 gene variant linked to higher cancer risk and mortality
A case-control study of over 636,000 adults from UK Biobank and Geisinger MyCode cohorts found heterozygous PALB2 pathogenic/likely pathogen…
A common gene variant called PALB2 is linked to higher odds of breast, pancreatic, and other cancers plus reduced survival compared to peopl…
Prediction model for 30-day mortality in cancer patients with carbapenem-resistant organism infections
Researchers develop model to predict death risk in cancer patients with resistant infections
A retrospective cohort study of 417 cancer patients with CRO infections at Henan Cancer Hospital developed a 14-factor prediction model for …
A new tool predicts which cancer patients with hard-to-treat infections face the highest risk of dying within 30 days by analyzing 14 key fa…
Survey finds 94% of cancer patients willing to try acupuncture for symptom relief
What do cancer patients want from acupuncture? A survey reveals their top hopes.
A questionnaire survey of 511 cancer patients at Beijing Cancer Hospital found 481 (94.1%) were willing to receive acupuncture treatment. Di…
Cancer patients overwhelmingly want acupuncture to help with sleep, pain, and fatigue, with 94% expressing willingness to try the treatment.
Pilot RCT finds mindfulness intervention feasible for chronic pain in cancer survivors
Can mindfulness help cancer survivors manage chronic pain? A small study explores.
A pilot randomized controlled trial of 60 cancer survivors with moderate-to-severe chronic pain tested three formats of Mindfulness-Oriented…
Cancer survivors with chronic pain reported less bothersome and severe pain after a short mindfulness program, though the study was too smal…
Literature review associates TIVA and regional anesthesia with better immune preservation in cancer surgery
Anesthesia choices during cancer surgery may affect immune function and recurrence risk
A literature review synthesizing clinical trials, cohort studies, and meta-analyses suggests total intravenous anesthesia with propofol and …
Choosing anesthesia with propofol and regional blocks may help preserve immune cells that fight cancer, while high-dose opioids can reduce t…
Surveillance summary describes health care provision for 9/11-related conditions
Health program continues providing care for 9/11 responders and survivors
This surveillance summary describes health care provision for 9/11-related health conditions through the World Trade Center Health Program s…
Since 2011, the World Trade Center Health Program has provided health care for 9/11-related conditions among responders and survivors.
Qigong shows large effect on subjective cognitive function in cancer survivors in meta-analysis
Can gentle movement help cancer survivors struggling with brain fog?
A systematic review and meta-analysis of 16 studies in cancer survivors found qigong significantly improved subjective cognitive function ve…
Cancer survivors struggling with brain fog may feel clearer after practicing qigong, a gentle mix of movement and breathing that showed stro…
Interactive e-books and traditional education show comparable effectiveness for foundational cancer sleep management nurse training
Study compares e-book and traditional training for nurses on cancer sleep management
A cluster randomized controlled trial of 142 oncology nurses found both interactive e-books and traditional education significantly improved…
Interactive e-books and traditional classes both boosted nurses' confidence in helping cancer patients with sleep issues, though knowledge g…
Systematic review finds first FDA-approved CRISPR therapy and broader clinical trial exploration
First CRISPR gene therapy approved for blood disorders, with broader research underway
A systematic review of clinical trials registered at clinicaltrials.gov found the first CRISPR-Cas9 therapy obtained FDA approval in late 20…
The first CRISPR gene therapy is approved for sickle-cell anemia and β-thalassemia, with ongoing trials exploring its use for cancer and inf…
Review examines reference gene selection methods for qRT-PCR normalization in cancer research
Review examines gene analysis methods for cancer research and precision medicine
A systematic review describes the progression of traditional and advanced reference gene selection methods for qRT-PCR normalization and the…
Accurate cancer research depends on picking the right reference genes, and new tools now help scientists choose them for better precision me…
Catheter ablation for atrial fibrillation in cancer patients shows non-significant bleeding trend
Catheter ablation for atrial fibrillation shows similar outcomes in cancer and non-cancer patients
A meta-analysis of 69,819 patients from eight observational studies compared catheter ablation outcomes in atrial fibrillation patients with…
Catheter ablation for atrial fibrillation works similarly in cancer and non-cancer patients, with a trend toward more bleeding in cancer sur…
Modeling study predicts human pharmacokinetics for TAK-500, an anti-CCR2 antibody-drug conjugate
Early modeling study predicts how a new cancer drug candidate might behave in humans
A preclinical and clinical modeling study used cynomolgus monkey data and human parental antibody data to simulate human pharmacokinetics fo…
A computer model predicts that a new cancer drug stays in the body longer as the dose increases, helping scientists plan safe first-in-human…